mendeley

    Advancements in Microemulsion Based Drug Delivery Systems for Better Therapeutic Effects

    DOI Logo 10.17352/ijpsdr.000003

    Published On: August 31, 2015 | Pages: 008 - 015

    Author(s): Gyanesh Kumar Sahu, Harish Sharma, Anshita Gupta and Chanchal Deep Kaur*
    Abstract Recent progress in combinatorial drug has led to the generation of a large number of new compounds. microemulsions are versatile systems of great technological and scientific interest to the researchers because of their potential to incorporate a wide range of drug molecules (hydrophilic and hydrophobic) due to the pres ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    mendeley

    A Pharmacokinetic Analysis and Pharmacogenomic Study of 6-mercaptopurine

    DOI Logo 10.17352/ijpsdr.000002

    Published On: May 23, 2015 | Pages: 002 - 007

    Author(s): Vicha A, Katsila T, Giannopoulou E, Leontari H, El Mubarak M, Gravia A, Chondrou V, Symeonidis A, Patrinos GP, Kalofonos HP and Sivolapenko G*
    Background: The efficacy and safety of 6-mercaptopurine (6-MP) therapy rely on the concentration of its metabolites. The aim of the current study is the pharmacokinetic analysis of 6-MP and the detection of its metabolites as well as the role of Thiopurine S-methyl transferase (TPMT), the enzyme associated with 6-MP metabolism, as a pharmacogenomics biomarker. ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Heat Shock Protein 90 c-Terminal Inhibitors in Cancer Treatment

    DOI Logo 10.17352/ijpsdr.000001

    Published On: May 16, 2015 | Pages: 001 - 001

    Author(s): Yusuf Tutar*
    Editorial Heat shock protein 90 (Hsp90) is 90 kDa highly conserved dimeric chaperone protein in prokaryotic and eukaryotic cells and it is localized in different parts of the cell. Hsp90AA1 (inducible) and Hsp90AB1 (constitutive) are available in the cytosol; Grp94 and TRAP1 exist in endoplasmic reticulum and mitochondria; respectively. In unstressed cells, express ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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